Informational
Biopolymers of Genes and Gene ExpressionInformational
Biopolymers of Genes and Gene Expression"Written
in a detailed but very accessible way, Blake's book plays down the use of
equations and formalisms so they don't get in the way of the narrative flow of
ideas and concepts. The comprehensive array of topics makes it
very attractive as both a reference text and a textbook for Physical
Biochemistry or Molecular Biology courses. It fills a real unmet need by
looking at a whole range of fashionable molecular biology topics with a rigor
that has never before been applied to these topics in one volume.”--- Ken
Marx, University of Massachusetts
"I
am blown away by this book: its scope, its level of detail, its up-to-date
coverage. It will be a valuable source to have on one's shelf to refer to
a concise discussion of a topic, with lots of references to the pertinent
literature." --- Victor Bloomfield, University of Minnesota
"Without doubt, this book will make a useful reference text for the expert and should provide a good text for teaching graduate students." ---Philip C. Bevilacqua, University of Pennsylvania
Full of novel insights informed by years of
research and teaching, R.D. Blake has written a new text that examines the
biophysics and biochemistry of nucleic acids and proteins. This book carves out
the dynamic interface between chemistry and molecular biology, and provides a
detailed picture of nucleic acids and proteins, their structures, biological
properties, and origins and evolution. While pitched at a level that is
accessible to upper-level undergraduate students of biology, the book will
likewise be of keen interest to researchers and graduate students in biology,
chemistry and the physical sciences. A broad range of topics accompanied with
extensive references, footnotes, boxed asides, chapter ending problems, and
detailed illustrations throughout combine to make this an ideal choice for
courses on advanced biochemistry, physical biochemistry, nucleic acids and
proteins, biophysics and biochemistry, molecular evolution, and protein-nucleic
acid interactions.
The Author:
R.D. Blake received his BS in biology and
chemistry at Tufts College, and Ph.D in biochemistry from Princeton University.
After a year of postdoctoral research at Princeton with Professor J.R. Fresco,
he continued as a member of the research staff for five years, following which
he joined the Biochemistry Department at the University of Maine. He has published papers on the thermodynamics of DNA, DNA
denaturation, the effects of solvents and denaturants on DNA stability,
macrosatellite evolution, and the effects of neutral drift on DNA sequence
complexity.
