Nucleic
Acids
Structures, Properties and Functions
Victor
A. Bloomfield, University of Minnesota
Donald
M. Crothers, Yale University
Ignacio Tinoco, Jr., University of California at Berkeley
"It was a
pleasure to review this book, which is a suitable textbook for graduate courses
in physical biochemistry. It provides an update for the widely used text
by Cantor and Schimmel...I would recommend this text for graduate classes in
physical biochemistry."
--Journal of the American Chemical Society (2000, 122 (46), pg. 11570)
"Overall,
this is an excellent book that should find use in graduate level biophysical
chemistry and physical biochemistry courses and as a reference for physical
chemists, physical biochemists, and molecular biologists."
--Journal of Medicinal Chemistry (2000, Vol. 43, No. 24, pg. 4721)
"This work effectively closes a gap in the scientific literature where a
comprehensive, updated book has been long overdue. Written by three
recognized worldwide experts in the field, the book acts as an up-to-date
encyclopedia of nucleic acids with an emphasis on implications for biological
functions."
--Drug Discovery Today
Nucleic
Acids presents an up-to-date and comprehensive account of the
structures and physical chemistry properties of nucleic acids,
with special emphasis on biological function. With a targeted
audience of 1)molecular biologists, 2)physical biochemists, and
3)physical chemists, the book has been carefully organized to
reach three different audiences while requiring only introductory
physical chemistry and molecular biology as prerequisites. Nucleic
Acids will serve as a textbook in physical biochemistry and
biophysical chemistry classes, as well as a supplemental text in
courses on nucleic acid biochemistry or molecular biology, and as
a personal reference for students and researchers in these
fields.
Key
Features
- Organized
according to a systematic consideration of techniques
used in the study of nucleic acid structure and
properties.
- Key
topics--such as protein-DNA and protein-drug complexes,
conformational transitions, characterization of nucleic
acids by gel and solution techniques, and behavior of
supercoiled DNA--are covered in great detail as veritable
mini-monographs.
- Heavily
illustrated with diagrams, graphs, and molecular
structures, including nearly 2 dozen color figures.
- Includes
numerous figures, tables and an extensive bibliography
to facilitate use as a reference volume.
ISBN 978-0-935702-49-1,
2000, 794 pages, color plates, clothbound
List Price US$98.00
Publisher's Discount Price US$83.30
