Chemistry, First Edition
The University of North Carolina at Chapel Hill
"Sorrell has produced
a unique organic chemistry textbook. He has managed to integrate an
enormous amount of biological material into the text and do it in a way that
successfully shows the relationship between simple organic reactions and complex
biological processes. This approach may well be the "new wave"
in organic texts, and Sorrell's effort deserves a serious look." --Journal
of Chemical Education
a tour de force. It should be the number one choice for courses
composed of the more capable undergraduates."
J. William Suggs, Brown University
is an exceptional text, one of the best I have ever read. The
text is both thorough and very well written. Biological examples
are incorporated throughout and give good incentive for
understanding the topics."
--Professor Tom Bond, University of California at San Diego
easy reading style and excellent examples related to biology will
engage my pre-med and biology majors. I like the fact that this
book treats these biological applications as "real"
organic chemistry. Biology IS organic chemistry!"
--Professor Andrew French, Albion College
brilliantly innovative textbook constructs organic chemistry from
the ground up. By focusing on the points of reactivities in
organic molecules -- showing why they are reactive, what kinds of
moieties react by certain pathways, and how surroundings may
alter the reactivity -- this text allows students to approach
more and more complex molecules with enhanced understanding. Also
noteworthy are the biochemical examples for their variety,
substance, and depth. Despite its unique emphasis on reactivity,
the book facilitates easy adoption by covering organic compound
classes in a traditional order. Hundreds of worked examples and
student exercises combine with clear writing and sound pedagogy
to make this text an exceptional choice.
Features of This Edition:
organic reactions by mechanism rather than by functional
complete and integrated treatment of biochemical
processes with organic reaction mechanisms. Highlights
include alcohol oxidation; squalene biosynthesis
(carbon-carbon bond formation via carbocations);
arachidonic acid reactions (radical cyclization
processes); amino acid metabolism (Schiff base
chemistry); peptide cleavage by serine proteases;
carbohydrate metabolism and biosynthesis (aldol
reaction); metabolism of fats (Claisen condensation);
drug detoxification and thymine biosynthesis (conjugate
new reactions such as the Swern oxidation, Mitsunobu
reaction, and Suzuki reaction, all presented at an
chemistry of free radicals: tributyltin hydride and its
use to initiate radical substitution and addition
reactions; enediyne compounds.
organometallic mechanisms: oxidative addition, reductive
elimination, migratory insertion. Examples used to
illustrate the basic concepts include hydrogenation of
alkenes with use of Wilkinson's catalyst, Ziegler-Natta
polymerization, and the Suzuki reaction.
reactions and synthesis: Sharpless epoxidation, Sharpless
asymmetric dihyroxylation; Jacobsen epoxidation;
enantioselective hydroboration; oxazaborolidine reagents
for ketone reduction; asymmetric amino acid synthesis.
topics of current (and future) interest including polymer
chemistry; enantioselective reactions and synthesis;
fullerenes; use of enzymes as reagents in synthesis;
combinatorial libraries; and molecular recognition.
To link to the
accompanying Solutions to Exercises by Sorrell,
transparency sets with more than 500 Figures and Tables from the
textbook are available to adopting professors. Click here for a
complete List of Transparencies
ISBN 0-935702-47-4, 1999, 1472 pages, clothbound
List Price US$106.00
Publisher's Discount Price US$90.10
Solutions Manual: ISBN 1-891389-08-4, 1999, set price includes
this text + the accompanying Solutions to Exercises (
712 pages, paperback)
List Price US$130
Publisher's Discount Price US$110.50